In der Prostata kaltsenat

Nanoknife IRE for Prostate Cancer

Uzi Größe der Prostata ist normal

Der Pathologe. Bei vielen Tumorentitäten, insbesondere der Mamma, versteht man unter einem intraduktalen Karzinom eine Vorläuferläsion, die fakultativ der Entstehung eines invasiven Karzinoms vorausgeht. Gerade auch in der Mammadiagnostik spielen Angaben zur Ausdehnung und Beschaffenheit einer intraduktalen Tumorkomponente neben den Parametern des invasiven Karzinoms seit jeher eine besondere, die Therapieplanung modulierende Rolle.

Anders verhält es sich bei der Prostata, in der Prostata kaltsenat der der gleiche Begriff zwar existiert und von wenigen seit längerem propagiert, aber dennoch selten und uneinheitlich verwendet wird. Dies liegt zum einen sicher in den vereinfachten Therapieoptionen des Prostatakarzinoms, bei dem fokale und organerhaltende Therapien eine bislang noch untergeordnete Rolle spielen, sicher aber auch in der erheblichen Interobservervariabilität und dem uneinheitlichen Verständnis des intraduktalen Karzinoms.

Dieser kleine Artikel will eine Übersicht über die gegenwärtige Literatur zum Thema geben und erläutern, warum es sich lohnt, diese Läsion zu diagnostizieren. Im Gegensatz zur Mamma stellt das intraduktale Karzinom bei der Prostata ganz überwiegend eine postinvasive Läsion dar, bei der ein dazu geeigneter, zumeist aggressiver Tumor in das präexistente Gangsystem einbricht. Seltener scheint es sich jedoch auch um eine echte Vorläuferläsion handeln zu können.

For many tumor entities, especially in breast cancer, an intraductal carcinoma is generally perceived as a precursor lesion, which precedes the emergence of invasive carcinoma. Therefore, in addition to in der Prostata kaltsenat of the invasive carcinoma, histological parameters of the intraductal component have always played an important role in therapy planning of breast cancer.

This is different in prostate cancer and although the term "intraductal carcinoma" has long been propagated by some authors, its routine use remains rare and inconsistent. This is certainly not only due to the far simpler therapy options of prostate cancer, in which focal and organ-preserving therapies still play a subordinate role, but also due in der Prostata kaltsenat substantial interobserver variation and our inconsistent perception of intraductal carcinomas.

This article gives a brief overview of currently available literature on this topic and explains in der Prostata kaltsenat intraductal carcinoma of the prostate deserves our attention. In contrast in der Prostata kaltsenat breast cancer, intraductal carcinoma of the prostate usually represents a post-invasive lesion, in which an aggressive tumor exhibits spread into pre-existing ducts; however, in rare cases, intraductal carcinoma may represent a true precursor lesion.

Kristiansen, M. Varma und G. Seitz geben an, dass kein Interessenkonflikt in der Prostata kaltsenat. Skip to in der Prostata kaltsenat content. Advertisement Hide. Intraduktales Karzinom der Prostata. Authors In der Prostata kaltsenat and affiliations G. Kristiansen M. Varma G. Schwerpunkt: Uropathologie First Online: 18 January Intraductal carcinoma of the prostate. This is a preview of subscription content, log in to check access.

Einhaltung ethischer Richtlinien Interessenkonflikt G. Anonymous Pathology and genetics of tumours of the urinary system and male genital organs. Prostate — CrossRef Google Scholar. Clouston D, Bolton D In situ and intraductal epithelial proliferations of prostate: definitions and treatment implications.

Part 2: intraductal carcinoma and ductal adenocarcinoma of prostate. Cohen RJ, Wheeler TM, Bonkhoff H et al A proposal on the identification, histologic reporting, and implications of in der Prostata kaltsenat prostatic carcinoma. Guo CC, Epstein JI Intraductal carcinoma of the prostate on needle biopsy: histologic features and clinical significance. Humphrey PA Intraductal carcinoma of the prostate. Iczkowski KA, Egevad L, Ma J et al Intraductal carcinoma of the prostate: interobserver reproducibility survey of 39 urologic pathologists.

Magers M, Kunju LP, Wu A Intraductal carcinoma of the prostate: morphologic features, differential in der Prostata kaltsenat, significance, and reporting practices. Morphologic and clinical correlations. Montironi R, Cheng L, Lopez-Beltran A et al A better understating of the morphological features and molecular characteristics of intraductal carcinoma helps clinicians further explain prostate cancer aggressiveness. Robinson BD, Epstein JI Intraductal in der Prostata kaltsenat of the prostate without invasive carcinoma on needle biopsy: emphasis on radical prostatectomy findings.

Sailer V, Kristiansen G Histopathological screening for prostate carcinoma: is a benign biopsy a negative biopsy? Shah RB, Zhou M Atypical cribriform lesions of the prostate: clinical significance, differential diagnosis and current concept of intraductal carcinoma in der Prostata kaltsenat the prostate.

Trudel D, Downes MR, Sykes J et al Prognostic in der Prostata kaltsenat of intraductal carcinoma and large cribriform carcinoma architecture after prostatectomy in a contemporary cohort. Tsuzuki T Intraductal carcinoma of the prostate: a comprehensive and updated review. Van Der Kwast T, Al Daoud N, Collette L et al Biopsy diagnosis of intraductal carcinoma is prognostic in intermediate and high risk prostate cancer patients treated by radiotherapy.

Watts K, Li J, Magi-Galluzzi C, Zhou M Incidence and clinicopathological characteristics of intraductal carcinoma detected in prostate biopsies: a prospective cohort study. Histopathology 63 4 — Google Scholar. Hum Pathol 29 10 — Google Scholar. Zhao T, Liao B, Yao J et al Is there any prognostic impact of intraductal carcinoma of prostate in initial diagnosed aggressively metastatic prostate cancer? Zhou M Intraductal carcinoma of the prostate: the whole story. Kristiansen 1 Email author M.

Varma 2 G. Seitz 3 1. Personalised recommendations. Cite article How to cite? ENW EndNote. Buy options.