Urologie - Aquablation zur Therapie der gutartigen Prostatavergrößerung
A gonadotropin-releasing hormone Peptide der Prostata GnRH agonist is a type of medication which affects gonadotropins and sex hormones. GnRH agonists are given by injections into fatas implants placed into fatand as nasal sprays.
Peptide der Prostata effects of GnRH agonists are related to sex hormone deficiency and include symptoms of low testosterone levels and low estrogen levels such as hot flashessexual dysfunctionvaginal atrophyosteoporosisinfertility Peptide der Prostata, and diminished sex-specific physical characteristics. They are agonists of the GnRH receptor and work by increasing or decreasing the release of gonadotropins and the production of sex hormones by the gonads.
The most well-known and Peptide der Prostata used GnRH analogue is leuprorelin brand name Lupron. GnRH analogues are available as generic medications.
Despite this however, they continue to be very expensive. Women of reproductive age who undergo cytotoxic chemotherapy have been pretreated with GnRH agonists to reduce the risk of oocyte loss during such therapy and preserve ovarian function. Further studies are necessary to prove that Peptide der Prostata approach is useful.
GnRH agonists that have been marketed and are available for medical use include buserelingonadorelingoserelinhistrelinleuprorelinnafarelinand triptorelin.
GnRH agonists that are used mostly or exclusively in veterinary medicine include deslorelin and fertirelin. GnRH agonists can be administered by injectionby implantor intranasally as a nasal spray.
Injectables have been formulated for daily, monthly, and quarterly use, and implants are available that can last from one month to a year. With the exception of gonadorelin, which is used as a progonadotropinall approved GnRH agonists are used as antigonadotropins.
The clinically used desensitizing GnRH agonists are available in the following pharmaceutical formulations :    . GnRH agonists are pregnancy category X drugs. Side effects of the GnRH agonists are signs and symptoms Peptide der Prostata hypoestrogenismincluding hot flashesheadaches, and osteoporosis.
Generally, long-term patients, both male and female, tend to undergo annual DEXA scans to appraise bone density. These drugs can be both peptides and small-molecules. They are modeled after the hypothalamic neurohormone GnRH, which interacts with the GnRH receptor to elicit its biologic response, the release of the pituitary hormones follicle-stimulating hormone FSH and luteinizing hormone LH.
Agonists do not quickly dissociate from the GnRH receptor. GnRH agonists are synthetically modeled after the natural GnRH decapeptide with Peptide der Prostata modifications, usually double and single substitutions and typically in position 6 amino acid substitution9 alkylation and Peptide der Prostata deletion. These substitutions inhibit rapid degradation.
Agonists with two substitutions include: leuprorelinbuserelinhistrelingoserelinand deslorelin. The agents nafarelin and triptorelin are agonists with single substitutions at position 6. GnRH analogues are also used in veterinary medicine.
Uses include:. From Wikipedia, the free encyclopedia. Gonadotropin-releasing Peptide der Prostata agonist Drug class Leuprorelinone of the most widely used GnRH agonists. Chemical structures of GnRH agonists. Gonadorelin GnRH. Indian Journal of Endocrinology and Metabolism. Principles and Practice of Endocrinology and Metabolism.
Fertility Control. CRC Press. Urologia Internationalis. Handbook of In Vitro Fertilization Fourth ed. Endocrinology: Adult and Pediatric E-Book. Elsevier Health Sciences. Seminars in Reproductive Medicine. The Journal of Sexual Medicine. Lehne; Laura Rosenthal 25 June Pharmacology for Nursing Care - Peptide der Prostata. Gulley 20 December Prostate Cancer. Demos Medical Publishing. Brook's Clinical Pediatric Endocrinology. Rev Urol. Eur Urol Focus. Initial administration of LHRH agonists reliably causes a transient rise in serum T, with peak T values observed at 2—4 d followed by a reduction to baseline values by 7—8 d, and achievement of castrate levels by 2—4 wk .
Human Reproduction. How serious is it? Drug Saf. Zoladex Study Group". Prostate Cancer Prostatic Dis. J Natl Compr Canc Peptide der Prostata. GnRH and gonadotropins. Follicle-stimulating hormone Human chorionic gonadotropin Luteinizing hormone Menotropin Urofollitropin. Sex steroid antagonists via disinhibition of the HPG axis : Antiandrogens e. Assisted reproductive technology. Female Male Fertility clinic Fertility testing Fertility tourism. Assisted zona hatching Autologous endometrial coculture Cytoplasmic transfer Embryo transfer Gestational carrier In vitro maturation Intracytoplasmic sperm injection Oocyte selection Ovarian hyperstimulation Preimplantation genetic diagnosis Snowflake children Transvaginal ovum retrieval Zygote intrafallopian transfer.
Artificial insemination Ovulation induction Cryopreservation embryos oocyte ovarian tissue semen Gamete intrafallopian transfer Reproductive surgery Vasectomy reversal Peptide der Prostata reduction Sex selection Surrogacy.
See subsection in sperm donation Reproduction and pregnancy in speculative fiction. GnRH and gonadotropin receptor modulators. Agonists: Peptides: Choriogonadotropin alfa Human chorionic gonadotropin Luteinizing hormone Lutropin alfa Menotropin human menopausal gonadotropin. Categories : Antiandrogens Antiestrogens Peptide der Prostata Fertility medicine Hormonal antineoplastic drugs Gonadotropin-releasing hormone and gonadotropins Progonadotropins Transgender and medicine.
In Wikidata. Breast cancer; Endometrial hyperplasia; Endometriosis; Female infertility assisted reproduction ; Prostate cancer; Uterine fibroids. Cryptorchidism; Delayed puberty; Diagnostic agent pituitary disorders ; Hypogonadotropic hypogonadism; Veterinary medicine assisted reproduction.
Breast cancer; Endometriosis; Female infertility assisted reproduction ; Prostate cancer; Uterine diseases endometrial thinning agent ; Peptide der Prostata fibroids; Uterine hemorrhage.
Breast cancer; Endometriosis; Female infertility assisted reproduction ; Paraphilias; Precocious puberty; Prostate cancer; Uterine fibroids. Sources: See individual articles. Preparations Follicle-stimulating hormone Human chorionic gonadotropin Luteinizing hormone Menotropin Urofollitropin.